+ |
Caspase-2 PIDDosome | up-regulates activity
cleavage
|
BID |
0.553 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262644 |
|
|
Homo sapiens |
|
pmid |
sentence |
20158568 |
Inactive caspase-2 monomers are recruited to the PIDDosome in response to certain cellular stresses. This results in dimerization and activation of caspase-2. Caspase-2 cleaves and activates Bid to induce MOMP eventually resulting in activation of executioner caspases by caspase-9-mediated cleavage. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CRADD | form complex
binding
|
Caspase-2 PIDDosome |
0.921 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262642 |
|
|
Homo sapiens |
|
pmid |
sentence |
20158568 |
The PIDDosome consists of the proteins PIDD, RAIDD and caspase-2. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CASP2 | form complex
binding
|
Caspase-2 PIDDosome |
0.858 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262641 |
|
|
Homo sapiens |
|
pmid |
sentence |
20158568 |
The PIDDosome consists of the proteins PIDD, RAIDD and caspase-2. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PIDD1 | form complex
binding
|
Caspase-2 PIDDosome |
0.845 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262643 |
|
|
Homo sapiens |
|
pmid |
sentence |
20158568 |
The PIDDosome consists of the proteins PIDD, RAIDD and caspase-2. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |