Summary

Name GATA2
Full Name Endothelial transcription factor GATA-2
Synonyms GATA-binding protein 2
Primary ID P23769
Links - -
Type protein
Relations 8
Pathways Adipogenesis, FAP: SHH, FAP: adipogenic transcriptional cascade, FAP: Notch
Function Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation GATA2 0.10
Publications: 1 Organism: Homo Sapiens
Pathways:Adipogenesis
+ down-regulates img/direct_inhibition.png phosphorylation GATA2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/indirect-activation.png unknown GATA2
Publications: 1 Organism: Mus Musculus
Pathways:FAP: SHH
+ down-regulates activity img/direct_inhibition.png unknown PPARG
Publications: 1
Pathways:Adipogenesis, FAP: adipogenic transcriptional cascade, FAP: Notch, FAP: SHH
+ up-regulates img/direct-activation.png phosphorylation GATA2 0.09
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png unknown GATA2 0.01
Publications: 1 Organism: Homo Sapiens
Pathways:Adipogenesis
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation GATA2 0.22
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png unknown Adipogenesis
Publications: 1 Organism: Homo Sapiens
Pathways:Adipogenesis, FAP: adipogenic transcriptional cascade, FAP: Notch, FAP: SHH