4.0
Myofiber: BMP
Pathway ID: SIGNOR-MB
Description: BMPs have an essential role during bone and cartilage formation and maintenance. Recently it was demonstrated that the BMP pathway also has a role in controlling adult skeletal muscle mass. Thus, BMPs are crucial regulators of both bone and muscle formation and homeostasis.Sartori & Sandri (PMID:26036170)
Curated by: Gianni Cesareni
Use SIGNOR Cytoscape App
Description: BMPs have an essential role during bone and cartilage formation and maintenance. Recently it was demonstrated that the BMP pathway also has a role in controlling adult skeletal muscle mass. Thus, BMPs are crucial regulators of both bone and muscle formation and homeostasis.Sartori & Sandri (PMID:26036170)
Curated by: Gianni Cesareni
Use SIGNOR Cytoscape App
16 Seed Entities
Organism: 
|
Name | Primary ID |
|---|---|
| mTORC1 | SIGNOR-C3 |
| BMP7 | P18075 |
| FBXO30 | Q8TB52 |
| SMAD1/5/8 | SIGNOR-PF35 |
| Muscle_atrophy | SIGNOR-PH40 |
| HDAC1 | Q13547 |
| FBXO32 | Q969P5 |
| MYOD1 | P15172 |
| Proliferation | SIGNOR-PH4 |
| BMPR1A | P36894 |
| NOG | Q13253 |
| FOXO | SIGNOR-PF27 |
| GDF5 | P43026 |
| SMAD1/5/8/SMAD4 | SIGNOR-C215 |
| BMPR1B | O00238 |
| BMPR1A/1B/2 | SIGNOR-C29 |