Myofiber: BMP
Pathway ID: SIGNOR-MB
Description: BMPs have an essential role during bone and cartilage formation and maintenance. Recently it was demonstrated that the BMP pathway also has a role in controlling adult skeletal muscle mass. Thus, BMPs are crucial regulators of both bone and muscle formation and homeostasis.Sartori & Sandri (PMID:26036170)
Curated by: Gianni Cesareni
Description: BMPs have an essential role during bone and cartilage formation and maintenance. Recently it was demonstrated that the BMP pathway also has a role in controlling adult skeletal muscle mass. Thus, BMPs are crucial regulators of both bone and muscle formation and homeostasis.Sartori & Sandri (PMID:26036170)
Curated by: Gianni Cesareni
16 Seed Entities
Organism: | Name | Primary ID |
---|---|
mTORC1 | SIGNOR-C3 |
BMP7 | P18075 |
FBXO30 | Q8TB52 |
SMAD1/5/8 | SIGNOR-PF35 |
Muscle_atrophy | SIGNOR-PH40 |
HDAC1 | Q13547 |
FBXO32 | Q969P5 |
MYOD1 | P15172 |
Proliferation | SIGNOR-PH4 |
BMPR1A | P36894 |
NOG | Q13253 |
FOXO | SIGNOR-PF27 |
GDF5 | P43026 |
SMAD1/5/8/SMAD4 | SIGNOR-C215 |
BMPR1B | O00238 |
BMPR1A/1B/2 | SIGNOR-C29 |