Pathway Browser

Myofiber: BMP

Type: Score: Layout: SPV 
0.6880.7740.5520.5490.7760.8560.6750.20.20.70.70.3730.70.20.20.7NOGGDF5BMP7BMPR1A/1B/2BMPR1ABMPR1BSMAD1/5/8SMAD1/5/8/SMAD4FOXOMYOD1mTORC1ProliferationMuscle_atrophyHDAC1FBXO32FBXO30
Pathway ID: SIGNOR-MB

Description: BMPs have an essential role during bone and cartilage formation and maintenance. Recently it was demonstrated that the BMP pathway also has a role in controlling adult skeletal muscle mass. Thus, BMPs are crucial regulators of both bone and muscle formation and homeostasis.Sartori & Sandri (PMID:26036170)

Curated by: Gianni Cesareni

16 Seed Entities

Organism:
Name Primary ID
mTORC1 SIGNOR-C3
BMP7 P18075
FBXO30 Q8TB52
SMAD1/5/8 SIGNOR-PF35
Muscle_atrophy SIGNOR-PH40
HDAC1 Q13547
FBXO32 Q969P5
MYOD1 P15172
Proliferation SIGNOR-PH4
BMPR1A P36894
NOG Q13253
FOXO SIGNOR-PF27
GDF5 P43026
SMAD1/5/8/SMAD4 SIGNOR-C215
BMPR1B O00238
BMPR1A/1B/2 SIGNOR-C29
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