| + |
MARCHF9 | down-regulates quantity by destabilization 
ubiquitination
|
HLA-DQB1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271539 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
VAMP8 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271531 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
SLAMF1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271537 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
PTPRA |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271540 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
PTPRJ |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271535 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
FCGR2B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271541 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
FCRL2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271543 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
CEMIP2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271533 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Ub:E2 | up-regulates activity 
ubiquitination
|
MARCHF9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271249 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
HLA-DQA1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271538 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
IGHD |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271542 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
LILRB1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271534 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
PVR |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271530 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
PLXNC1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271532 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MARCHF9 | down-regulates quantity by destabilization
ubiquitination
|
PTPRF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271536 |
|
|
Homo sapiens |
B-lymphocyte Cell Line |
| pmid |
sentence |
| 19457934 |
MARCH9, a member of the RING-CH family of transmembrane E3 ubiquitin ligases, down-regulates CD4, major histocompatibility complex-I (MHC), and ICAM-1 in lymphoid cells. To identify novel MARCH9 substrates, we used high throughput flow cytometry and quantitative mass spectrometry by stable isotope labeling by amino acids in cell culture (SILAC) to determine the differential expression of plasma membrane proteins in a MARCH9-expressing B cell line. This combined approach identified 13 potential new MARCH9 targets. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MARCHF9
- 
- 