Summary

Name GNG12
Full Name Guanine nucleotide-binding protein G
Synonyms GBG12_HUMAN
Primary ID Q9UBI6
Links - -
Type protein
Relations 9
Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding PI3K
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNG12 0.53
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png chemical activation GNG12
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PLCE1 0.62
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNG12 0.33
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding AKT2 0.55
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNG12 0.04
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PIK3CA 0.07
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding PRKACA 0.51
Publications: 1 Organism: Homo Sapiens