Summary

Name AMOT
Full Name Angiomotin
Synonyms AMOT_HUMAN | KIAA1071
Primary ID Q4VCS5
Links - -
Type protein
Relations 4
Function Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png relocalization YAP1 0.34
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png relocalization WWTR1 0.34
Publications: 2 Organism: Homo Sapiens