+ |
AMOT | down-regulates
relocalization
|
WWTR1 |
0.668 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-201132 |
|
|
Homo sapiens |
|
pmid |
sentence |
23431053 |
Yap/taz and angiomotin (amot) family proteins were shown to interact, resulting in yap/taz localization to tight junctions and inhibition through phosphorylation-dependent and -independent mechanisms. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-175776 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
21205866 |
Our results indicate a potential tumor-suppressing role of AMOT family proteins as components of the Hippo pathway, and demonstrate a novel mechanism of YAP and TAZ inhibition by AMOT-mediated tight junction localization. These observations provide a potential link between the Hippo pathway and cell contact inhibition. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
+ |
AMOT | down-regulates
relocalization
|
YAP1 |
0.728 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-175779 |
|
|
Homo sapiens |
|
pmid |
sentence |
21808241 |
Yap/taz and angiomotin (amot) family proteins were shown to interact, resulting in yap/taz localization to tight junctions and inhibition through phosphorylation-dependent and -independent mechanisms. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-201135 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
21205866 |
Our results indicate a potential tumor-suppressing role of AMOT family proteins as components of the Hippo pathway, and demonstrate a novel mechanism of YAP and TAZ inhibition by AMOT-mediated tight junction localization. These observations provide a potential link between the Hippo pathway and cell contact inhibition. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |