Inhibition of Apoptosis

Pathway ID: SIGNOR-IOAView in NDEx

Description: Apoptosis needs to be tightly regulated. Survival signals such as growth factors activates pathways that inhibit pro-apoptotic proteins and activates anti-apoptotic factors.

Curated by: Alessandra Silvestri

32 Seed Entities

Organism:
Name Primary ID
PARP1 P09874
RPS6KA1 Q15418
BCL2 P10415
MEK1/2 SIGNOR-PF25
BAD Q92934
GRB2 P62993
XIAP P98170
Caspase 7 complex SIGNOR-C232
TRAF2 Q12933
CASP9 P55211
CREB1 P16220
MAP3K7 O43318
NFKBIA P25963
BAX Q07812
TNF P01375
BCL2L11 O43521
NRAS P01111
IKK-complex SIGNOR-C14
Survival SIGNOR-PH13
BRAF P15056
NfKb-p65/p50 SIGNOR-C13
Apoptosis SIGNOR-PH2
TNFRSF1A P19438
FOXO3 O43524
Survival Factors SIGNOR-ST8
ERK1/2 SIGNOR-PF1
CASP3 P42574
TRADD Q15628
SOS1 Q07889
AKT SIGNOR-PF24
CASP7 P55210
FOXO1 Q12778