Summary

Name KLF5
Full Name Krueppel-like factor 5
Synonyms Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, Transcription factor BTEB2 | BTEB2, CKLF, IKLF
Primary ID Q13887
Links - -
Type protein
Relations 7
Pathways Adipogenesis, FAP: Adipogenic transcriptional cascade, FAP: Notch
Function Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation KLF5 0.341
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation KLF5 0.375
Publications: 1 Organism: Homo Sapiens
Pathways:Adipogenesis
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination KLF5 0.495
Publications: 1 Organism: Chlorocebus Aethiops
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation KLF5 0.297
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ up-regulates img/indirect-activation.png transcriptional regulation PPARG 0.607
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLF5 0.691
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLF5 0.504
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis