Summary

Name KLF5
Full Name Krueppel-like factor 5
Synonyms Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, Transcription factor BTEB2 | BTEB2, CKLF, IKLF
Primary ID Q13887
Links - -
Type protein
Relations 9
Pathways Adipogenesis, FAP: Adipogenic transcriptional cascade, FAP: Notch
Function Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.

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▶Modifications Tables

Relations

Regulator Mechanism target score ℹ
+ PRKCDup-regulates activity img/direct-activation.png phosphorylation KLF5 0.334
Publications: 1 Organism: Homo Sapiens
+ GSK3Bdown-regulates img/direct_inhibition.png phosphorylation KLF5 0.367
Publications: 1 Organism: Homo Sapiens
Pathways:Adipogenesis
+ WWP1up-regulates activity img/direct-activation.png ubiquitination KLF5 0.458
Publications: 1 Organism: Homo Sapiens
+ KLF5up-regulates img/indirect-activation.png transcriptional regulation PPARG 0.625
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ SMURF2down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination KLF5 0.369
Publications: 1 Organism: Homo Sapiens
+ CEBPDup-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLF5 0.527
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ TRIM25down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination KLF5 0.481
Publications: 1 Organism: Chlorocebus Aethiops
+ CEBPBup-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLF5 0.704
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis
+ NR3C1up-regulates quantity by expression img/direct-activation.png transcriptional regulation KLF5 0.292
Publications: 1 Organism: Mus Musculus
Pathways:Adipogenesis