Neurotransmitters release

Pathway ID: SIGNOR-NR

Description: Presynaptic active zones consist of a highly specialized network of proteins that acts in neurotransmitter release. The key function of the active zone is to organize the fusion process that is mediated by SNARE proteins and triggered by calcium to render it highly temporally and spatially precise.

Curated by: Marta Iannuccelli

36 Seed Entities

Organism:
Name Primary ID
DNM1 Q05193
SYBU Q9NX95
STXBP1 P61764
RIMS1 Q86UR5
calcium(2+) CHEBI:29108
SNARE_complex SIGNOR-C346
SYT1 P21579
SNX9 Q9Y5X1
PKA SIGNOR-PF17
APBA1 Q02410
CTNNB1 P35222
STON2 Q8WXE9
VAMP2 P63027
CAMK2A Q9UQM7
Synaptic_vesicle_recycling SIGNOR-PH161
ITPR1 Q14643
Cadherins SIGNOR-PF71
STX1A Q16623
Synaptic_vesicle_exocytosis SIGNOR-PH160
3',5'-cyclic AMP CHEBI:17489
UNC13B O14795
GNAI1 P63096
ADCY1 Q08828
Dense-core_vesicle_exocytosis SIGNOR-PH184
SV2A Q7L0J3
CSNK2A1 P68400
NRXN1 Q9ULB1
CACNA1A O00555
GPCR SIGNOR-PF33
SCRIB Q14160
RAB3A P20336
SNAP25 P60880
SNCA P37840
SYP P08247
SYN1 P17600
DAPK1 P53355