Summary

Name ADCY1
Full Name Adenylate cyclase type 1
Synonyms ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclase
Primary ID Q08828
Links - -
Type protein
Relations 23
Pathways WNT Signaling, WNT Signaling and Myogenesis
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding ADCY1 0.23
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding ADCY1 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding ADCY1 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding ADCY1 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding ADCY1 0.23
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png small molecule catalysis 3',5'-cyclic AMP 0.37
Publications: 3 Organism: Homo Sapiens, Mus Musculus
+ down-regulates img/direct_inhibition.png binding ADCY1 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png ADCY1 0.23
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding ADCY1 0.34
Publications: 2 Organism: Mus Musculus, Homo Sapiens
Pathways:WNT Signaling, WNT Signaling and Myogenesis
+ up-regulates img/indirect-activation.png ADCY1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png ADCY1 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding ADCY1 0.23
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding ADCY1 0.23
Publications: 1 Organism: Homo Sapiens