Summary

Name VAV1
Full Name Proto-oncogene vav
Synonyms VAV_HUMAN | VAV
Primary ID P15498
Links - -
Type protein
Relations 18
Function Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation VAV1 0.22
Publications: 3 Organism: In Vitro
+ up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAC1 0.46
Publications: 1 Organism: Drosophila Melanogaster
+ up-regulates activity img/direct-activation.png binding VAV1 0.46
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation VAV1 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png MAPK1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation VAV1 0.58
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation VAV1 0.36
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png PRKCQ 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding CBL 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GRB2 0.57
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png ERK1/2 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding SYK 0.49
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GRAP 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding VAV1 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates img/direct-activation.png phosphorylation VAV1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png binding VAV1 0.14
Publications: 1 Organism: Homo Sapiens