Satellite: TNFA

Pathway ID: SIGNOR-ScTNFA

Description: Tumor necrosis factor (TNF)-alpha is a potent mitogen during the muscle regeneration process, being able to modulate satellite cell proliferation and differentiation. Proliferation is linked to the NF-kB regulation and the activation of p38/MAPK14 with the chromatin redistribution of PRC2.

Curated by: Simone Vumbaca

17 Seed Entities

Organism:
Name Primary ID
YY1 P25490
NfKb-p65/p50 SIGNOR-C13
TRADD Q15628
TNFRSF1A P19438
MYOD1 P15172
Proliferation SIGNOR-PH4
Skeletal_muscle_differentiation SIGNOR-PH1
NFKBIA P25963
Polycomb repressive complex 2 SIGNOR-C130
PAX7 P23759
RIPK1 Q13546
ZFP36 P26651
TNF P01375
IKK-complex SIGNOR-C14
MAPK14 Q16539
Quiescence SIGNOR-PH25
TRAF2 Q12933