Summary

Name EZR
Full Name Ezrin
Synonyms Cytovillin, Villin-2, p81 | VIL2
Primary ID P15311
Links - -
Type protein
Relations 18
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.31
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EZR 0.23
Publications: 3 Organism: Homo Sapiens
Tissue: Kidney
+ img/unknown.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation EZR 0.14
Publications: 1 Organism: In Vitro
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png transcriptional activation EZR 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png relocalization FES 0.31
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Metastasis 0.14
Publications: 1 Organism: Homo Sapiens