Summary

Name WNT3A
Full Name Protein Wnt-3a
Synonyms WNT3A_HUMAN
Primary ID P56704
Links - -
Type protein
Relations 25
Pathways WNT Signaling, WNT Signaling and Myogenesis
Function Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png palmitoylation WNT3A 0.28
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding FZD1 0.28
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding LRP5 0.50
Publications: 2 Organism: Homo Sapiens
Pathways:WNT Signaling, WNT Signaling and Myogenesis
+ up-regulates activity img/direct-activation.png relocalization WNT3A 0.28
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png WNT3A 0.14
Publications: 2 Organism: Homo Sapiens
Pathways:WNT Signaling
+ up-regulates quantity by stabilization img/direct-activation.png stabilization FBN1 0.08
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding LRP6 0.78
Publications: 3 Organism: Homo Sapiens
Pathways:WNT Signaling, WNT Signaling and Myogenesis
+ up-regulates activity img/direct-activation.png binding Frizzled 0.28
Publications: 2 Organism: Homo Sapiens,
Pathways:WNT Signaling, WNT Signaling and Myogenesis
+ down-regulates img/indirect_inhibition.png WNT3A 0.14
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding FZD3 0.14
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png ALPL 0.08
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/indirect-activation.png DVL1 0.08
Publications: 1 Organism: Homo Sapiens
Pathways:WNT Signaling, WNT Signaling and Myogenesis
+ up-regulates img/direct-activation.png binding RYK 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding FZD2 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding WNT3A 0.08
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png WNT3A 0.08
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding FZD8 0.22
Publications: 1 Organism: Homo Sapiens