Summary

Name HIST1H3A
Full Name Histone H3.1
Synonyms Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l | H3FA, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
Primary ID P68431
Links - -
Type protein
Relations 26
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png trimethylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.23
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.24
Publications: 4 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.24
Publications: 4 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: In Vitro
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png acetylation HIST1H3A 0.14
Publications: 1 Organism: Homo Sapiens