Summary

Name STAT5A
Full Name Signal transducer and activator of transcription 5A
Synonyms STA5A_HUMAN | STAT5
Primary ID P42229
Links - -
Type protein
Relations 51
Pathways Acute Myeloid Leukemia, AML1-ETO in AML, FLT3 in AML, miRNA in AML, BCR-ABL in AML, KIT in AML
Inhibitors ponatinib
Function Carries out a dual function

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
+ up-regulates img/direct-activation.png phosphorylation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
+ up-regulates img/direct-activation.png phosphorylation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation STAT5A 0.46
Publications: 1 Organism: Mus Musculus
Pathways:Acute Myeloid Leukemia, FLT3 in AML, miRNA in AML
+ up-regulates img/direct-activation.png phosphorylation STAT5A 0.42
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation STAT5A 0.22
Publications: 1 Organism: Chlorocebus Aethiops
+ up-regulates activity img/direct-activation.png phosphorylation STAT5A 0.14
Publications: 1 Organism: In Vitro
+ up-regulates img/direct-activation.png phosphorylation STAT5A 0.7
Publications: 4 Organism: Saccharomyces Cerevisiae, Homo Sapiens
Pathways:Acute Myeloid Leukemia, AML1-ETO in AML, BCR-ABL in AML, KIT in AML
+ up-regulates activity img/direct-activation.png dephosphorylation STAT5A 0.14
Publications: 1 Organism: In Vitro
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation miR-155 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:miRNA in AML
+ up-regulates img/indirect-activation.png transcriptional regulation Adipogenesis 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation STAT5A 0.22
Publications: 1 Organism: Mus Musculus
Pathways:Acute Myeloid Leukemia, BCR-ABL in AML
+ down-regulates img/indirect_inhibition.png Cell death 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png FOXP3 0.14
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Erythrocyte differentiation 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation PIM1 0.2
Publications: 2 Organism: , Homo Sapiens
+ up-regulates img/indirect-activation.png Proliferation 0.55
Publications: 3 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, AML1-ETO in AML, BCR-ABL in AML, FLT3 in AML, KIT in AML, miRNA in AML
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation MEF2C 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding STAT5A 0.52
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation PIM2 0.14
Publications: 1
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation IRF5 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding STAT5A 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png STAT5A 0.31
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Survival 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ up-regulates quantity img/direct-activation.png transcriptional activation DNMT3A 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, miRNA in AML
+ up-regulates img/indirect-activation.png STAT5A 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding STAT5A 0.28
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation STAT5A 0.7
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, AML1-ETO in AML, BCR-ABL in AML, KIT in AML
+ up-regulates img/direct-activation.png binding STAT5A 0.31
Publications: 1 Organism: Homo Sapiens
Tissue: Breast
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation PIM 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, FLT3 in AML
+ down-regulates img/direct_inhibition.png dephosphorylation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding NR3C1/STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PIM 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, FLT3 in AML
+ down-regulates img/indirect_inhibition.png Apoptosis 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, AML1-ETO in AML, BCR-ABL in AML, FLT3 in AML, KIT in AML, miRNA in AML
+ down-regulates activity img/direct_inhibition.png chemical inhibition STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png oxidation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HBA1 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png dephosphorylation STAT5A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation IGF1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HBB 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates img/indirect-activation.png M1 polarization 0.14
Publications: 1 Organism: Homo Sapiens