COVID-19 Causal Network

Pathway ID: SIGNOR-CCN
View in NDEx

Curated by: Marta Iannuccelli

complexity level

level 1 seed interactions
level 2 connect
level 3 first neighbors
level 4 all
level 5 PPI
WORK IN PROGRESS...

157 Seed Entities

Organism:
Name Primary ID
PARP1 P09874
BCL2 P10415
PABPC1 P11940
XBP1 P17861-2
ORF4b K9N643
SACM1L Q9NTJ5
BCL2L1 Q07817
PPP1CC P36873
TYK2 P29597
CREB1 P16220
MAP3K7 O43318
TBK1 Q9UHD2
Receptor_mediated_ endocytosis SIGNOR-PH121
Viral_replication SIGNOR-ST23
IL1B P01584
RACK1 P63244
8b Q80H93
CTSB P07858
FAS P25445
3b P59633
Proliferation SIGNOR-PH4
NLRP3 inflammasome SIGNOR-C225
PPP1R15A O75807
EIF4EBP1 Q13541
Inflammation SIGNOR-PH12
TGFb SIGNOR-PF5
CASP8 Q14790
ERK1/2 SIGNOR-PF1
IL6 P05231
ATF4 P18848
MCL1 Q07820
CASP3 P42574
REN P00797
Camostat CID:2536
AGTR2 P50052
MEK1/2 SIGNOR-PF25
N P0DTC9
ATF2 P15336
SDCBP O00560
Unfolded_Proteins SIGNOR-ST22
PI4KB Q9UBF8
Fibrosis SIGNOR-PH90
CASP9 P55211
G3BP2 Q9UN86
SMAD3/SMAD4 SIGNOR-C9
STING1 Q86WV6
CYCS P99999
Interferon-type-I SIGNOR-PF50
MAP2K3 P46734
EIF4E P06730
TLRs SIGNOR-PF20
MAP2K7 O14733
Apoptosis SIGNOR-PH2
FLNA P21333
LARP4B Q92615
Membrane_fusion SIGNOR-PH122
TRAF3 Q13114
MAVS Q7Z434
IKBKE Q14164
APAF1 O14727
FADD Q13158
ISGF3 complex SIGNOR-C124
Uridylate-specific endoribonuclease P0C6X7-PRO_0000037321
TRADD Q15628
BID P55957
ATF6 P18850
MAS1 P04201
EGFR P00533
FASLG P48023
ACE2 Q9BYF1
8a Q7TFA0
DDX1 Q92499
SMAD7 O15105
TGFBR1 P36897
CoV2 Spike protein-ACE2 SIGNOR-C254
BAD Q92934
MYD88 Q99836
3a P59632
ACE P12821
DDIT3 P35638
GRB2 P62993
MAP3K1 Q13233
EGF P01133
PI3K SIGNOR-C156
6 P59634
9b P59636
CCL2 P13500
IFIH1 Q9BYX4
EP300 Q09472
NFKBIA P25963
EIF2AK3 Q9NZJ5
TGFBR2 P37173
BAX Q07812
RIPK1 Q13546
JAK1 P23458
TNF P01375
BCL2L11 O43521
IKK-complex SIGNOR-C14
ER stress SIGNOR-ST9
p38 SIGNOR-PF16
NfKb-p65/p50 SIGNOR-C13
RAF1 P04049
TNFRSF1A P19438
MAP2K4 P45985
Immune_response SIGNOR-PH17
AP-2/clathrin vescicle SIGNOR-C249
M P59596
IL18 Q14116
4E2RCat CID:2287236
Stress_granules SIGNOR-PH124
SERPINE1 P05121
TGFB1 P01137
SOS1 Q07889
CSNK2A1 P68400
AKT SIGNOR-PF24
AGTR1 P30556
IFITMs SIGNOR-PF49
IRF3 Q14653
S P59594
TRAF6 Q9Y4K3
JNK SIGNOR-PF15
HSPA5 P11021
TICAM1 Q8IUC6
CTSL P07711
Angiotensin-2 P01019-PRO_0000032458
MAP2K6 P52564
PRKACA P17612
PAMPs SIGNOR-ST11
Angiotensin 1-7 P01019-PRO_0000420660
7b Q7TFA1
7a P59635
PPP2CA P67775
G3BP1 Q13283
DDX58 O95786
Protein_synthesis SIGNOR-PH29
N P59595
Papain-like proteinase P0C6X7-PRO_0000037311
ERN1 O75460
EIF2AK2 P19525
phosphatidylinositol 4-phosphate CHEBI:37530
Angiotensin-1 P01019-PRO_0000032457
S P0DTC2
chloroquine CHEBI:3638
AP1 SIGNOR-C154
SMAD3 P84022
KRAS P01116
MAPK8 P45983
CASP6 P55212
DDX21 Q9NR30
Viral_dsRNA SIGNOR-ST21
IFNAR SIGNOR-C243
aloxistatin CHEBI:101381
Caspase 1 complex SIGNOR-C220
TMPRSS2 O15393
AGT P01019
E P59637
EIF2S1 P05198